Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease

RecruitingOBSERVATIONAL
Enrollment

76

Participants

Timeline

Start Date

August 30, 2018

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Alzheimer's DiseaseLewy Body DementiaParkinson's Disease
Interventions
RADIATION

DaTscan

A functional imaging of the dopamine transporter using the radioligand \[123I\]FP-CIT

RADIATION

F18-AV-45

A brain scan to to measure the extent of amyloid deposition

RADIATION

FDG-PET

a brain scan measuring total and regional cerebral glucose metabolism wtih positron emission tomographs with 2-(18F)

GENETIC

APOE genotype

10 ml of whole blood will be drawn and shipped to Athena Diagnostics for genetic testing.

PROCEDURE

Polysomnogram

Overnight sleep study

BEHAVIORAL

Clinical Assessment

Clinical assessments include cognitive, behavioral, and motor evaluations

Trial Locations (1)

43210

RECRUITING

The Ohio State University, Columbus

All Listed Sponsors
collaborator

Avid Radiopharmaceuticals

INDUSTRY

collaborator

Mangurian Foundation

UNKNOWN

lead

Douglas Scharre

OTHER