Gentamicin for RDEB

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

February 2, 2017

Primary Completion Date

May 5, 2018

Study Completion Date

August 31, 2018

Conditions
Recessive Dystrophic Epidermolysis Bullosa
Interventions
DRUG

Gentamicin Sulfate

Participants will be divided into three cohorts: topical gentamicin; Topical gentamicin with microneedle roller assistance; IV gentamicin. While the intervention is the same drug, the topical gentamicin is compounded into a 0.5% ointment and the IV gentamicin is prepared to 7.5 mg/kg body weight and administered over a 30 minutes.

Trial Locations (1)

90033

University of Southern California, Los Angeles

All Listed Sponsors
lead

University of Southern California

OTHER

NCT03012191 - Gentamicin for RDEB | Biotech Hunter | Biotech Hunter