Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

intravenous infusion of 2 mg trospium chloride in 20 ml saline within 60 min and 240 ml tap water p.o

oral administration of 30 mg trospium chloride with 240 ml tap water

oral administration of 300 mg ranitidine with 240 ml tap water

oral administration of 500 mg clarithromycin with 240 ml tap water