Probiotics That Moderate pH and Antagonize Pathogens to Promote Oral Health

NACompletedINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

February 22, 2017

Primary Completion Date

June 25, 2020

Study Completion Date

June 25, 2020

Conditions
Dental Caries
Interventions
OTHER

Caries Free 1.5% Arginine

Study toothpaste assigned containing 1.5% Arginine. Subjects will also receive a Colgate Wave Comfort Adult Toothbrush to brush their teeth with twice a day.

OTHER

Caries Free Placebo Sodium Fluoride

Marketed Toothpaste containing 1100 ppm F as Sodium Fluoride will be assigned. Subjects will also receive a Colgate Wave Comfort Adult Toothbrush to brush their teeth with twice a day.

OTHER

Caries Active 1.5% Arginine

Study toothpaste assigned containing 1.5% Arginine. Subjects will also receive a Colgate Wave Comfort Adult Toothbrush to brush their teeth with twice a day.

OTHER

Caries Active- Placebo Sodium Fluoride

Marketed Toothpaste containing 1100 ppm F as Sodium Fluoride will be assigned. Subjects will also receive a Colgate Wave Comfort Adult Toothbrush to brush their teeth with twice a day.

Trial Locations (1)

32610

University of Florida College of Dentistry, Gainesville

All Listed Sponsors
collaborator

National Institute of Dental and Craniofacial Research (NIDCR)

NIH

lead

University of Florida

OTHER

NCT02999230 - Probiotics That Moderate pH and Antagonize Pathogens to Promote Oral Health | Biotech Hunter | Biotech Hunter