100
Participants
Start Date
March 16, 2017
Primary Completion Date
September 30, 2025
Study Completion Date
September 30, 2025
Randomized Cohort
Surgical treatment with different approach, based on the characteristics of the tumor or definitive high dose radiotherapy (carbon ion radiotherapy, proton-therapy, mixed photons-proton therapy) will be assigned by randomization
Prospective cohort
Surgical treatment or definitive high dose radiotherapy will be selected by the patients and will be prospectively evaluated
RECRUITING
EBG GmbH MedAustron, Wiener Neustadt
RECRUITING
Istituto Clinico Humanitas, Milan
RECRUITING
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
ACTIVE_NOT_RECRUITING
I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan
RECRUITING
Centro Nazionale di Adroterapia Oncologica - CNAO, Pavia
ACTIVE_NOT_RECRUITING
Agenzia Provinciale per la Protonterapia - AtreP, Trento
RECRUITING
Istituto Ortopedico Rizzoli, Bologna
NOT_YET_RECRUITING
Hospital Universitario Doctor Peset, Valencia
NOT_YET_RECRUITING
Azienda Ospedaliero-Universitaria Careggi, Florence
RECRUITING
II Clinica Universitaria Ortopedia e Traumatologia AO Pisa, Pisa
RECRUITING
Medical University of Graz, Graz
NOT_YET_RECRUITING
Medical Faculty Carl Gustav Carus Faculty of Medicine, Department of Radiation Oncology,, Dresden
NOT_YET_RECRUITING
University Hospital Carl Gustav Carus Dresden, Dresden
RECRUITING
University Hospital Essen. West German Proton Therapy Center Essen, Essen
NOT_YET_RECRUITING
Heidelberg Ion-Beam Therapy Center - HIT, Heidelberg
NOT_YET_RECRUITING
National Center for Spinal Disorders, Budapest
RECRUITING
Saitama Medical Center, Saitama
NOT_YET_RECRUITING
Netherlands Cancer Institute, Amsterdam
NOT_YET_RECRUITING
Leiden University Medical Center, Leiden
ACTIVE_NOT_RECRUITING
Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie, Warsaw
RECRUITING
H. Val D'Hebron, Barcelona
ACTIVE_NOT_RECRUITING
Hosptial San Pau, Barcelona
NOT_YET_RECRUITING
H. San Carlos, Madrid
RECRUITING
Hospital Universitario Virgen del Rocío, Seville
NOT_YET_RECRUITING
The Royal Orthopaedic Hospital, Birmingham
NOT_YET_RECRUITING
Royal National Orthopaedic Hospital, London
RECRUITING
Istituto Regina Elena - IFO, Rome
RECRUITING
Norwegian Radium Hospital/Oslo Univeristi Hospital, Oslo
Italian Sarcoma Group
NETWORK