Artery Function Responses to Changes in Blood Flow

NACompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

January 31, 2017

Primary Completion Date

March 31, 2017

Study Completion Date

March 31, 2017

Conditions
Endothelial Dysfunction
Interventions
OTHER

Suprasystolic (300 mmHg) cuff compressions

10 minutes of ECG-gated repeated suprasystolic (300 mmHg) cuff compressions, with inflation occurring every other heart cycle. These cuff compressions may be triggered 0 seconds, 0.2 seconds, or 0.4 seconds from the R spike (systole) on the ECG signal.

OTHER

Handgrip exercise

10 minutes of ECG-gated rhythmic handgrip exercise at 30% maximal voluntary contraction, with contraction occurring every other heart cycle

OTHER

Passive heat stress

10 minutes of passive heat stress at 42 degrees Celsius with a commercially available heating blanket

Trial Locations (1)

L8S 4L8

McMaster University Vascular Dynamics Lab, Hamilton

All Listed Sponsors
collaborator

Natural Sciences and Engineering Research Council, Canada

OTHER

lead

McMaster University

OTHER

NCT02982044 - Artery Function Responses to Changes in Blood Flow | Biotech Hunter | Biotech Hunter