Optimal Timing of Intercostal Nerve Blocks During Video-Assisted Thoracic Surgeries

PHASE4CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

September 28, 2016

Primary Completion Date

March 30, 2022

Study Completion Date

March 30, 2022

Conditions
Video-Assisted Thoracic SurgeryVideo-Assisted Thoracoscopic Surgery
Interventions
DRUG

Normal Saline

Blocking the nerves between the ribs with a local anesthetic is normally done as a part of routine care at the end of the surgery in one set of injections. Intervention group will receive injectate A at the beginning and injectate B and C prior to the closure. Control group receive injectate B at the beginning of surgery and injectate A and C prior to the closure and end of surgery. Injectate B contains 10 mL of 0.9% normal saline.

DRUG

Ropivacaine

Blocking the nerves between the ribs with a local anesthetic is normally done as a part of routine care at the end of the surgery in one set of injections. Intervention group will receive injectate A at the beginning and injectate B and C prior to the closure. Control group receive injectate B at the beginning of surgery and injectate A and C prior to the closure and end of surgery. Injectate A and C contain 9 and 24 mL of ropivacaine HCl 0.5%, respectively.

DRUG

Epinephrine

Blocking the nerves between the ribs with a local anesthetic is normally done as a part of routine care at the end of the surgery in one set of injections. Intervention group will receive injectate A at the beginning and injectate B and C prior to the closure. Control group receive injectate B at the beginning of surgery and injectate A and C prior to the closure and end of surgery. Injectate C contains 0.125 mL of epinephrine-1:1000 preparation.

DRUG

Dexamethasone

Blocking the nerves between the ribs with a local anesthetic is normally done as a part of routine care at the end of the surgery in one set of injections. Intervention group will receive injectate A at the beginning and injectate B and C prior to the closure. Control group receive injectate B at the beginning of surgery and injectate A and C prior to the closure and end of surgery. Injectates A and C both contain 1 mL of dexamethasone 4mg/mL preparation.

Trial Locations (1)

14215

VA Western New York Healthcare System, Buffalo

All Listed Sponsors
collaborator

The VA Western New York Healthcare System

FED

lead

University at Buffalo

OTHER

NCT02980835 - Optimal Timing of Intercostal Nerve Blocks During Video-Assisted Thoracic Surgeries | Biotech Hunter | Biotech Hunter