Immunization Strategy With Intra-tumoral Injections of Pexa-Vec With Ipilimumab in Metastatic / Advanced Solid Tumors.

PHASE1CompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

January 3, 2017

Primary Completion Date

April 13, 2022

Study Completion Date

June 6, 2022

Conditions
Metastatic TumorAdvanced Tumor
Interventions
BIOLOGICAL

Pexa-Vec

IT Injections will be performed by a radiologist using imaging-guidance, ultrasound or computed tomography (CT). The dose to be injected could be divided between 1 to 5 tumor lesions.

DRUG

Ipilimumab

IT Injections will be performed by a radiologist using imaging-guidance, ultrasound or computed tomography (CT). The dose to be injected could be divided between 1 to 5 tumor lesions.

Trial Locations (5)

33076

Institut Bergonie, Bordeaux

69008

Centre Léon Bérard, Lyon

69310

Centre Hospitalier Lyon Sud, Pierre-Bénite

75475

Hopital Saint Louis, Paris

Unknown

Institut Gustave Roussy, Villejuif

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Transgene

INDUSTRY

lead

Centre Leon Berard

OTHER