140
Participants
Start Date
April 11, 2017
Primary Completion Date
December 31, 2023
Study Completion Date
December 31, 2025
Endoscopic polypectomy in clinic (EPIC)
The experimental intervention is endoscopic polypectomy performed in clinic (EPIC) where nasal polyps are removed using a microdebrider under local and topical anesthesia in the outpatient clinic.
Endoscopic Sinus Surgery (ESS)
The control intervention is endoscopic sinus surgery (ESS), a minimally invasive procedure that is the current standard that involves polypectomy with a microdebrider as well as sinus ostia enlargement of the affected sinuses performed in the operating room under general anesthesia.
General Anesthesia
ESS will be performed under general anesthesia in the operating room
Local and topical anesthesia
EPIC will be performed under topical and local anesthesia in a clinic setting
RECRUITING
Vancouver General Hospital, Vancouver
RECRUITING
St. Joseph's Hospital London, London
RECRUITING
Ottawa Hospital Research Institute, Ottawa
RECRUITING
McGill University Health Center, Montreal
Lead Sponsor
Collaborators (1)
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
Medtronic
INDUSTRY
Ottawa Hospital Research Institute
OTHER