In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps

NARecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

April 11, 2017

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2025

Conditions
SinusitisNasal Polyps
Interventions
PROCEDURE

Endoscopic polypectomy in clinic (EPIC)

The experimental intervention is endoscopic polypectomy performed in clinic (EPIC) where nasal polyps are removed using a microdebrider under local and topical anesthesia in the outpatient clinic.

PROCEDURE

Endoscopic Sinus Surgery (ESS)

The control intervention is endoscopic sinus surgery (ESS), a minimally invasive procedure that is the current standard that involves polypectomy with a microdebrider as well as sinus ostia enlargement of the affected sinuses performed in the operating room under general anesthesia.

OTHER

General Anesthesia

ESS will be performed under general anesthesia in the operating room

OTHER

Local and topical anesthesia

EPIC will be performed under topical and local anesthesia in a clinic setting

Trial Locations (4)

Unknown

RECRUITING

Vancouver General Hospital, Vancouver

N6A 4V2

RECRUITING

St. Joseph's Hospital London, London

K1Y 1J8

RECRUITING

Ottawa Hospital Research Institute, Ottawa

H4A 3J1

RECRUITING

McGill University Health Center, Montreal

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

Medtronic

INDUSTRY

lead

Ottawa Hospital Research Institute

OTHER