20
Participants
Start Date
October 20, 2016
Primary Completion Date
July 18, 2020
Study Completion Date
July 18, 2020
Baseline Biopsy
Baseline biopsy (and ascites fluid sampling if applicable). This is done during the normal work-up procedures.
Tissue Collection
Tissue collection during debulking surgery.
Blood Draws
Blood samples for paclitaxel and carboplatin plasma levels will be collected in the study. Paclitaxel will be measured on cycle 1 day 1 at predose and then at the end of the infusion, followed by 1, 2, 4, 8 hours after the end of infusion, then on cycle 1 day 2 at 24 hours after the end of infusion. Carboplatin will be sampled for on cycle 1 day 1 at predose and then at the end of the infusion, followed by 0.5, 1.5, 3.5, 7.5 hours after the end of infusion, then on cycle 1 day 2 at 23.5 hours after the end of infusion.
H. Lee Moffitt Cancer Center and Research Institute, Tampa
The V Foundation for Cancer Research
OTHER
Kay Yow Cancer Fund
UNKNOWN
H. Lee Moffitt Cancer Center and Research Institute
OTHER