Laryngeal Reinnervation Versus Thyroplasty in Patients With Vocal Fold Weakness.

PHASE2CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

May 31, 2016

Primary Completion Date

April 30, 2018

Study Completion Date

April 30, 2018

Conditions
Vocal Cord Paralysis Unilateral
Interventions
PROCEDURE

Thyroplasty

This medialisation/augmentation technique is a static technique, performed under local anaesthesia that aims to improve the positioning of the paralysed vocal fold. It uses a silastic implant readily available in different sizes according to size of larynx and gender of the patient. The correct size can be determined intraoperatively by using a measuring device while listening and visualising the larynx with flexible fiberoptic scope simultaneously.

PROCEDURE

Reinnervation

For laryngeal reinnervation, ansa cervicalis to recurrent laryngeal nerve repair technique will be used. In this technique, the functioning ansa cervicalis nerve that overlies the internal jugular vein and the distal stump of injured recurrent laryngeal nerve (RLN) will be identified and anastomosed without tension (Crumley RL. Teflon versus thyroplasty versus nerve transfer: a comparison. The Annals of otology, rhinology, and laryngology. 1990;99(10 Pt 1):759-63).

Trial Locations (1)

WC1X 8DA

Royal National Throat Nose and Ear Hospital, 330 Gray's Inn Road, London

All Listed Sponsors
collaborator

University College Joint Research Office

UNKNOWN

collaborator

University College London Hospitals

OTHER

collaborator

National Institute for Health Research, United Kingdom

OTHER_GOV

collaborator

Sealed Envelope: Redpill Online Application

UNKNOWN

lead

Royal National Throat, Nose and Ear Hospital

OTHER

NCT02973152 - Laryngeal Reinnervation Versus Thyroplasty in Patients With Vocal Fold Weakness. | Biotech Hunter | Biotech Hunter