Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department

PHASE4TerminatedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

April 24, 2017

Study Completion Date

April 24, 2017

Conditions

Headache, Migraine

Interventions

DRUG

Metoclopramide

Patients receive 10 mg of intravenous (IV) metoclopramide.

DRUG

Haloperidol

Patients receive 2.5 mg of IV haloperidol.

OTHER

Normal Saline

All patients receive a 1-liter bolus of normal saline (NS)

DRUG

Diphenhydramine

All patients receive 25 mg of intravenous (IV) diphenhydramine.

Trial Locations (1)

OhioHealth Doctors Hospital, Columbus