NCT02970942View on ClinicalTrials.gov

Investigation of Efficacy and Safety of Three Dose Levels of Subcutaneous Semaglutide Once Daily Versus Placebo in Subjects With Non-alcoholic Steatohepatitis.

PHASE2CompletedINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

November 30, 2016

Primary Completion Date

February 13, 2020

Study Completion Date

March 19, 2020

Conditions
Hepatobiliary DisordersNon-alcoholic Steatohepatitis
Interventions
DRUG

Semaglutide

Once daily administration of semaglutide subcutaneously (s.c., under the skin) in three different doses (0.1 mg, 0.2 mg and 0.4 mg)

DRUG

Placebo

Once daily administration subcutaneously ( s.c., under the skin)

Trial Locations (158)

1030

Novo Nordisk Investigational Site, Vienna

1070

Novo Nordisk Investigational Site, Brussels

1200

Novo Nordisk Investigational Site, Brussels

1407

Novo Nordisk Investigational Site, Sofia

1431

Novo Nordisk Investigational Site, Sofia

2050

Novo Nordisk Investigational Site, Camperdown

2145

Novo Nordisk Investigational Site, Westmead

2650

Novo Nordisk Investigational Site, Edegem

Novo Nordisk Investigational Site, Hvidovre

2747

Novo Nordisk Investigational Site, Kingswood

3065

Novo Nordisk Investigational Site, Fitzroy

3128

Novo Nordisk Investigational Site, Box Hill

5020

Novo Nordisk Investigational Site, Salzburg

8036

Novo Nordisk Investigational Site, Graz

8200

Novo Nordisk Investigational Site, Aarhus N

9000

Novo Nordisk Investigational Site, Ghent

10676

Novo Nordisk Investigational Site, Athens

11030

Novo Nordisk Investigational Site, Manhasset

13285

Novo Nordisk Investigational Site, Marseille

14186

Novo Nordisk Investigational Site, Stockholm

15213

Novo Nordisk Investigational Site, Pittsburgh

15706

Novo Nordisk Investigational Site, Santiago de Compostela

21202

Novo Nordisk Investigational Site, Baltimore

23249

Novo Nordisk Investigational Site, Richmond

25000

Novo Nordisk Investigational Site, Besançon

28034

Novo Nordisk Investigational Site, Madrid

28222

Novo Nordisk Investigational Site, Majadahonda

31059

Novo Nordisk Investigational Site, Toulouse

32207

Novo Nordisk Investigational Site, Jacksonville

32610

Novo Nordisk Investigational Site, Gainesville

33014

Novo Nordisk Investigational Site, Miami

33136

Novo Nordisk Investigational Site, Miami

33434

Novo Nordisk Investigational Site, Boca Raton

33604

Novo Nordisk Investigational Site, Pessac

34090

Novo Nordisk Investigational Site, Montpellier

34211

Novo Nordisk Investigational Site, Lakewood Rch

34240

Novo Nordisk Investigational Site, Sarasota

34761

Novo Nordisk Investigational Site, Ocoee

35233

Novo Nordisk Investigational Site, Birmingham

37076

Novo Nordisk Investigational Site, Hermitage

39008

Novo Nordisk Investigational Site, Santander

41013

Novo Nordisk Investigational Site, Seville

46026

Novo Nordisk Investigational Site, Valencia

48202

Novo Nordisk Investigational Site, Detroit

55905

Novo Nordisk Investigational Site, Rochester

63003

Novo Nordisk Investigational Site, Clermont-Ferrand

68198

Novo Nordisk Investigational Site, Omaha

69200

Novo Nordisk Investigational Site, Vénissieux

69317

Novo Nordisk Investigational Site, Lyon

71201

Novo Nordisk Investigational Site, Monroe

75230

Novo Nordisk Investigational Site, Dallas

75571

Novo Nordisk Investigational Site, Paris

75651

Novo Nordisk Investigational Site, Paris

77030

Novo Nordisk Investigational Site, Houston

77058

Novo Nordisk Investigational Site, Houston

78229

Novo Nordisk Investigational Site, San Antonio

78731

Novo Nordisk Investigational Site, Austin

78746

Novo Nordisk Investigational Site, Rollingwood

85224

Novo Nordisk Investigational Site, Chandler

85712

Novo Nordisk Investigational Site, Tucson

89106

Novo Nordisk Investigational Site, Las Vegas

89109

Novo Nordisk Investigational Site, Las Vegas

90057

Novo Nordisk Investigational Site, Los Angeles

91325

Novo Nordisk Investigational Site, Northridge

91402

Novo Nordisk Investigational Site, Panorama City

91942

Novo Nordisk Investigational Site, La Mesa

92118

Novo Nordisk Investigational Site, Coronado

92377

Novo Nordisk Investigational Site, Rialto

92627

Novo Nordisk Investigational Site, Costa Mesa

98104

Novo Nordisk Investigational Site, Seattle

111123

Novo Nordisk Investigational Site, Moscow

121170

Novo Nordisk Investigational Site, Moscow

121293

Novo Nordisk Investigational Site, Moscow

123423

Novo Nordisk Investigational Site, Moscow

125367

Novo Nordisk Investigational Site, Moscow

190013

Novo Nordisk Investigational Site, Saint Petersburg

194356

Novo Nordisk Investigational Site, Saint Petersburg

194358

Novo Nordisk Investigational Site, Saint Petersburg

195067

Novo Nordisk Investigational Site, Saint Petersburg

197110

Novo Nordisk Investigational Site, Saint Petersburg

197342

Novo Nordisk Investigational Site, Saint Petersburg

199226

Novo Nordisk Investigational Site, Saint Petersburg

355017

Novo Nordisk Investigational Site, Stavropol

355035

Novo Nordisk Investigational Site, Stavropol

410039

Novo Nordisk Investigational Site, Saratov

410053

Novo Nordisk Investigational Site, Saratov

420012

Novo Nordisk Investigational Site, Kazan'

424004

Novo Nordisk Investigational Site, Yoshkar-Ola

432063

Novo Nordisk Investigational Site, Ulyanovsk

440026

Novo Nordisk Investigational Site, Penza

630005

Novo Nordisk Investigational Site, Novosibirsk

630099

Novo Nordisk Investigational Site, Novosibirsk

634028

Novo Nordisk Investigational Site, Tomsk

650066

Novo Nordisk Investigational Site, Kemerovo

656045

Novo Nordisk Investigational Site, Barnaul

660022

Novo Nordisk Investigational Site, Krasnoyarsk

17822-2111

Novo Nordisk Investigational Site, Danville

75390-9302

Novo Nordisk Investigational Site, Dallas

05401

Novo Nordisk Investigational Site, Burlington

T2N 4Z6

Novo Nordisk Investigational Site, Calgary

R3E 3P4

Novo Nordisk Investigational Site, Winnipeg

B3H 2Y9

Novo Nordisk Investigational Site, Halifax

L6T 0G1

Novo Nordisk Investigational Site, Brampton

L8S 4K1

Novo Nordisk Investigational Site, Hamilton

N6A 5A5

Novo Nordisk Investigational Site, London

M5G 2C4

Novo Nordisk Investigational Site, Toronto

M6H 3M1

Novo Nordisk Investigational Site, Toronto

H4A 3J1

Novo Nordisk Investigational Site, Montreal

00290

Novo Nordisk Investigational Site, Helsinki

06202

Novo Nordisk Investigational Site, Nice

GR-11527

Novo Nordisk Investigational Site, Athens

GR-115 27

Novo Nordisk Investigational Site, Goudi, Athens

GR-41110

Novo Nordisk Investigational Site, Larissa

GR-54621

Novo Nordisk Investigational Site, Thessaloniki

GR-54642

Novo Nordisk Investigational Site, Thessaloniki

078-8510

Novo Nordisk Investigational Site, Asahikawa-shi, Hokkaido

918-8503

Novo Nordisk Investigational Site, Fukui-shi, Fukui

602-8566

Novo Nordisk Investigational Site, Kamigyo-ku, Kyoto

862-8655

Novo Nordisk Investigational Site, Kumamoto-shi, Kumamoto

480-1195

Novo Nordisk Investigational Site, Nagakute-shi, Aichi

630-8305

Novo Nordisk Investigational Site, Nara-shi, Nara

663-8501

Novo Nordisk Investigational Site, Nishinomiya-shi, Hyogo

545-8586

Novo Nordisk Investigational Site, Osaka-shi, Osaka

520-0804

Novo Nordisk Investigational Site, Otsu-shi, Shiga

849-8501

Novo Nordisk Investigational Site, Saga-shi, Saga

750-0061

Novo Nordisk Investigational Site, Shimonoseki-shi, Yamaguchi

564-0013

Novo Nordisk Investigational Site, Suita-shi, Osaka

565-0862

Novo Nordisk Investigational Site, Suita-shi, Osaka

760-8557

Novo Nordisk Investigational Site, Takamatsu-shi, Kagawa

470-1192

Novo Nordisk Investigational Site, Toyoake-shi, Aichi

1815 JD

Novo Nordisk Investigational Site, Alkmaar

1186 AM

Novo Nordisk Investigational Site, Amstelveen

1105 AZ

Novo Nordisk Investigational Site, Amsterdam

2625 AD

Novo Nordisk Investigational Site, Delft

9713 GZ

Novo Nordisk Investigational Site, Groningen

2333 ZA

Novo Nordisk Investigational Site, Leiden

6229 HX

Novo Nordisk Investigational Site, Maastricht

6525 GA

Novo Nordisk Investigational Site, Nijmegen

00927

Novo Nordisk Investigational Site, San Juan

413 45

Novo Nordisk Investigational Site, Gothenburg

205 02

Novo Nordisk Investigational Site, Malmo

112 81

Novo Nordisk Investigational Site, Stockholm

B15 2TH

Novo Nordisk Investigational Site, Birmingham

B9 5SS

Novo Nordisk Investigational Site, Birmingham

BL4 0JR

Novo Nordisk Investigational Site, Bolton

CB2 2QQ

Novo Nordisk Investigational Site, Cambridge

DE22 3NE

Novo Nordisk Investigational Site, Derby

DD1 9SY

Novo Nordisk Investigational Site, Dundee

EH16 4SA

Novo Nordisk Investigational Site, Edinburgh

G31 2ER

Novo Nordisk Investigational Site, Glasgow

HU3 2GZ

Novo Nordisk Investigational Site, Hull

LS9 7TF

Novo Nordisk Investigational Site, Leeds

NW3 2QG

Novo Nordisk Investigational Site, London

SE1 7EH

Novo Nordisk Investigational Site, London

SE5 9RS

Novo Nordisk Investigational Site, London

NG7 2UH

Novo Nordisk Investigational Site, Nottingham

PO6 3LY

Novo Nordisk Investigational Site, Portsmouth

SA2 8PP

Novo Nordisk Investigational Site, Swansea

Sponsors

Lead Sponsor

Novo Nordisk A/S
All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY