Use of Repetitive Transcranial Magnetic Stimulation to Augment Hypnotic Analgesia

NACompletedINTERVENTIONAL
Enrollment

101

Participants

Timeline

Start Date

April 24, 2017

Primary Completion Date

December 21, 2019

Study Completion Date

December 21, 2019

Conditions
Fibromyalgia
Interventions
DEVICE

MagPro TMS system (MagVenture, Denmark)

The investigators will perform two applications of 40s of continuous theta-burst stimulation (cTBS) form of rTMS at 80% resting motor threshold (previously determined), with a 15 minute intersession interval. The standardized treatment location for the left DLPFC will be determined by Localite Neuronavigation and targeted at the posterior middle frontal gyrus. The baseline structural scan obtained during the scan 1 will be utilized for this localization process. rTMS will be delivered using a MagPro TMS system (MagVenture, Denmark). sham rTMS will be delivered using a MagPro TMS system (MagVenture, Denmark).sham rTMS will be delivered using a MagPro TMS system (MagVenture, Denmark).

BEHAVIORAL

Hypnosis

Hypnotizability will be measured using the Hypnotic Induction Profile before and after administration of real vs. sham rTMS. Hypnotizability will be measured using the Hypnotic Induction Profile before and after administration of real vs. sham rTMS. Hypnosis will be employed to influence Stroop performance (conflict detection) and for pain management. The hypnotic instructions for this will be pre-recorded and played during fMRI.

Trial Locations (1)

94305

Stanford University, Palo Alto

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Center for Complementary and Integrative Health (NCCIH)

NIH

lead

Stanford University

OTHER

NCT02969707 - Use of Repetitive Transcranial Magnetic Stimulation to Augment Hypnotic Analgesia | Biotech Hunter | Biotech Hunter