568
Participants
Start Date
February 17, 2017
Primary Completion Date
August 11, 2020
Study Completion Date
August 21, 2024
Spartalizumab
Spartalizumab powder for solution is used in Part 1 and Part 2, and as concentrate for solution for infusion for Part 3. Spartalizumab is administered via intravenous infusion over 30 minutes once every 4 weeks
Placebo
Placebo is administered via intravenous infusion over 30 minutes once every 4 weeks
Dabrafenib
Dabrafenib 150 mg capsules BID is administered orally for Days 1-28 of a 28-day cycle, in fasting conditions.
Trametinib
Trametinib 2 mg tablets QD is administered orally for Days 1-28 of a 28-day cycle, in fasting conditions
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