Effect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD)

PHASE2CompletedINTERVENTIONAL
Enrollment

274

Participants

Timeline

Start Date

November 30, 2016

Primary Completion Date

August 31, 2019

Study Completion Date

September 30, 2019

Conditions
Cardiovascular DiseasesCardiovascular AbnormalitiesCalcifications, VascularEndstage Renal DiseaseESRDCoronary Artery Calcification
Interventions
DRUG

SNF472

Administered 3 times weekly by intravenous infusion through the dialysis machine in conjunction with the patient's dialysis sessions.

DRUG

Placebo

Administered 3 times weekly by intravenous infusion through the dialysis machine in conjunction with the patient's dialysis sessions.

Trial Locations (75)

10461

The Bronx

11356

College Point

14004

Córdoba

18017

Bethlehem

23320

Chesapeake

25008

Lleida

25198

Lleida

27003

Lugo

28040

Madrid

28801

Asheville

31008

Navarro

33011

Oviedo

33024

Hollywood

33133

Miami

33169

Miami Gardens

33614

Tampa

34471

Ocala

37923

Knoxville

39008

Santander

39601

Brookhaven

41007

Seville

45267

Cincinnati

46010

Valencia

46017

Valencia

48066

Roseville

48341

Pontiac

48960

Galdakao

50009

Zaragoza

53226

Wauwatosa

60201

Evanston

71101

Shreveport

75080

Richardson

76015

Arlington

77024

Houston

77099

Houston

78207

San Antonio

80002

Arvada

80031

Westminster

89106

Las Vegas

89511

Reno

90048

Los Angeles

90262

Lynwood

90603

Whittier

90623

La Palma

90807

Long Beach

91324

Northridge

91344

Granada Hills

91356

Tarzana

91773

San Dimas

91910

Chula Vista

92025

Escondido

92111

San Diego

92505

Riverside

93065

Simi Valley

93308

Bakersfield

06762

Middlebury

06477

Orange

33313-1638

Lauderdale Lakes

08902

North Brunswick

07011

Palma

07120

Palma

07198

Palma de Mallorca

08025

Barcelona

08003

Barcelona

08035

Barcelona

08036

Barcelona

08208

Barcelona

08970

Barcelona

07300

Palma

BD5 0NA

Bradford

M13 9WL

Manchester

M6 8HD

Salford

SY3 8XQ

Shrewsbury

SA6 6NL

Swansea

SS0 0RY

Westcliff-on-Sea

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Clinipace Worldwide

INDUSTRY

lead

Sanifit Therapeutics S. A.

OTHER