Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntington´s Disease Gene Expansion Carriers

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

September 6, 2015

Primary Completion Date

October 5, 2017

Study Completion Date

October 5, 2017

Conditions
Huntington's Disease
Interventions
RADIATION

Radioligand [18F]MNI-659

The effective radiation dose for the injection of \[18F\]MNI-659 is approximately 5.6 mSv (approximately 2 years of background radiation in Sweden) for an average person weighing 70 kg.

Trial Locations (7)

Unknown

The Memory Clinic, Rigshopitalet, Copenhagen

Uppsala University Hospital, Uppsala

K5Q112

Leiden University Medical Center, Department of Neurology, Leiden

0372 Oslo

University of Oslo, Nevrologisk poliklinikk, Oslo

SE-221 85

Skane Universitetssjukhus Lund, Neurologiska kliniken, Lund

SE-141 86

Karolinska Universitetssjukhus, Huddinge, Stockholm

SE-171 76

Karolinska University Hospital, Stockholm

All Listed Sponsors
lead

CHDI Foundation, Inc.

OTHER

NCT02956148 - Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntington´s Disease Gene Expansion Carriers | Biotech Hunter | Biotech Hunter