192
Participants
Start Date
December 14, 2016
Primary Completion Date
March 16, 2022
Study Completion Date
March 16, 2022
Midazolam
Single dose of 100 mcg midazolam solution will be administered orally, before (Day -1) and after (Day 14) the treatment with RO7049389 or matching placebo
Placebo
Placebo matching to RO7049389 will be administered as per schedule described in individual arm.
RO7049389
RO7049389 will be administered as per schedule described in individual arm.
Taipei Veterans General Hospital, Taipei
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City
Auckland Clinical Studies Limited, Grafton
Acibadem City Clinic Tokuda Hospital Ead, Sofia
Royal Melbourne Hospital, Parkville
Royal Brisbane and Women's Hospital, Herston
King Chulalongkorn Memorial Hospital, Bangkok
Siriraj Hospital, Bangkok
Taichung Veterans Gen Hosp, Taichung
Maharaj Nakorn Chiang Mai Hospital, Chiang Mai
National Cheng Kung University Hospital, Tainan City
National University Health System, Singapore
Singapore General Hospital, Singapore
Shanghai Jiao Tong University School of Medicine (SJTUSM) - Ruijin Hospital (GuangCi Hospital), Shanghai
Huashan Hospital Affiliated to Fudan University, Shanghai
Nanfang Hospital, Southern Medical University, Guangzhou
The University of Hong Kong; Queen Mary Hospital, Hong Kong
Prince of Wales Hospital, Shatin, New Territories
Middlemore Hospital, Auckland
Chang Gung Memorial Hospital - Kaohsiung Branch, Kaohsiung City
Chang Gung Memorial Hospital - Linkou Branch, Taipei
Hoffmann-La Roche
INDUSTRY