Abuse Liability of Reduced Nicotine Content Cigarettes Within a Complex Tobacco Marketplace

NACompletedINTERVENTIONAL
Enrollment

305

Participants

Timeline

Start Date

January 31, 2017

Primary Completion Date

November 30, 2019

Study Completion Date

November 30, 2019

Conditions
Substance-Related Disorders
Interventions
DRUG

SPECTRUM cigarettes

Across six laboratory sessions, participants will consume 10 puffs of either their usual brand of cigarette (one session) or a SPECTRUM cigarette (five sessions) with a nicotine yield varying from 0.03 to 0.70 and either menthol (TPMF codes NRC 103, NRC 201, NRC 301, NRC 401, and NRC 601) or tobacco (TPMF codes NRC 102, NRC 200, NRC 300, NRC 400, and NRC 600) flavor, depending on preference. This will be followed by the collection of blood nicotine content and a cigarette purchase task.

DRUG

SPECTRUM cigarettes between

Participants will be assigned one of the nicotine concentrations of a SPECTRUM cigarette. They will complete a cigarette purchase task and make real purchases for the next week. Participants will return and make purchases again, repeating 4 times.

Trial Locations (1)

24016

Fralin Biomedical Research Institute at VTC, Roanoke

All Listed Sponsors
collaborator

University of Kentucky

OTHER

lead

Virginia Polytechnic Institute and State University

OTHER

NCT02951143 - Abuse Liability of Reduced Nicotine Content Cigarettes Within a Complex Tobacco Marketplace | Biotech Hunter | Biotech Hunter