Using Preimplantation Genetic Diagnosis in Autosomal Dominant Polycystic Kidney Disease Patients: a Multicenter Clinical Trial

NACompletedINTERVENTIONAL
Enrollment

459

Participants

Timeline

Start Date

September 2, 2016

Primary Completion Date

November 30, 2020

Study Completion Date

December 31, 2020

Conditions
Polycystic Kidney, Type 1 Autosomal Dominant Disease
Interventions
PROCEDURE

Preimplantation Genetic Diagnosis

Using Preimplantation genetic diagnosis, including multiple annealing and looping-based amplification cycles amplification technique, the investigators have had screened out healthy embryos by In Vitro Fertilization. Then the investigators transplanted embryos returned to the parent. Finally, participants will have healthy baby without pathogenic gene inheritance.

Trial Locations (31)

100000

Navy General Hospital, Beijing

Peking University Third Hospital, Beijing

110000

Shengjing Hospital, Shenyang

200000

Shanghai Changzheng Hospital, Shanghai

210000

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Nanjing

The First Affiliated Hospital with Nanjing Medical University, Nanjing

215000

The First Affiliated Hospital of Soochow University, Suzhou

230000

The First Affiliated Hospital of Anhui Medical University, Hefei

250000

Hospital for Reproductive Medicine Affiliated to Shandong University, Jinan

Shandong Provincial Hospital, Jinan

310000

Sir Run Run Shaw Hospital of Zhejiang University, Hangzhou

350000

Fuzhou General Hospital, Fuzhou

400000

Southwest Hospital, Chongqing

410000

Reproductive & Genetic Hospital of CITIC-Xiangya, Changsha

Second Xiangya Hospital of Central South University, Changsha

Xiangya Hospital of Central South University, Changsha

430000

Renmin Hospital of Wuhan University, Wuhan

Wuhan Tongji Hospital, Wuhan

Wuhan Union Hospital, Wuhan

450000

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

510000

Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou

The First Affiliated Hospital of Sun Yat-sen University, Guangzhou

610000

Shanxi Provincial People's Hospital, Chengdu

West China Hospital of Sichuan University, Chengdu

West China Second University Hospital, Chengdu

710000

Tang-Du Hospital, Xi’an

730000

The First Hospital of Lanzhou University, Lanzhou

050000

Hebei Province Center for Reproductive Medicine, Shijiazhuang

The Second Hospital of Hebei Medical University, Shijiazhuang

The Third Hospital of Hebei Medical University, Shijiazhuang

030000

Shanxi Provincial People's Hospital, Taiyuan

All Listed Sponsors
collaborator

The First Affiliated Hospital of Anhui Medical University

OTHER

collaborator

The First Affiliated Hospital with Nanjing Medical University

OTHER

collaborator

Shandong Provincial Hospital

OTHER_GOV

collaborator

Tang-Du Hospital

OTHER

collaborator

Shengjing Hospital

OTHER

collaborator

Second Xiangya Hospital of Central South University

OTHER

collaborator

Reproductive & Genetic Hospital of CITIC-Xiangya

OTHER

collaborator

Peking University Third Hospital

OTHER

collaborator

Navy General Hospital, Beijing

OTHER

collaborator

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

OTHER

collaborator

The First Affiliated Hospital of Soochow University

OTHER

collaborator

Sir Run Run Shaw Hospital

OTHER

collaborator

Fuzhou General Hospital

OTHER

collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

collaborator

Wuhan TongJi Hospital

OTHER

collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

collaborator

Renmin Hospital of Wuhan University

OTHER

collaborator

Xiangya Hospital of Central South University

OTHER

collaborator

First Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

collaborator

Southwest Hospital, China

OTHER

collaborator

LanZhou University

OTHER

collaborator

Shaanxi Provincial People's Hospital

OTHER

collaborator

West China Hospital

OTHER

collaborator

West China Second University Hospital

OTHER

collaborator

Sichuan Provincial People's Hospital

OTHER

collaborator

Hebei Medical University Third Hospital

OTHER

collaborator

Hebei Province Center for Reproductive Medicine

UNKNOWN

collaborator

The Second Hospital of Hebei Medical University

OTHER

collaborator

Hospital for Reproductive Medicine Affiliated to Shandong University

UNKNOWN

lead

Changlin Mei

OTHER

NCT02948179 - Using Preimplantation Genetic Diagnosis in Autosomal Dominant Polycystic Kidney Disease Patients: a Multicenter Clinical Trial | Biotech Hunter | Biotech Hunter