Half Dose of Prasugrel and Ticagrelor in Acute Coronary Syndrome (HOPE-TAILOR)

PHASE3CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

September 30, 2016

Primary Completion Date

February 29, 2020

Study Completion Date

June 30, 2020

Conditions
Acute Coronary Syndrome
Interventions
DRUG

Clopidogrel 75 mg

Clopidogrel 600 mg as loading dose followed by 75 mg/day as maintenance dose.

DRUG

Prasugrel 5 mg

Loading / maintenance dose: prasugrel 60 mg / 10 mg/day; After 1-month treatment of conventional dose, followed half dose of 5 mg/day for chronic treatment.

DRUG

Ticagrelor 45 mg

Loading / maintenance dose: ticagrelor 180 mg / 90 mg/bid; After 1-month treatment of conventional dose, followed half dose of 45 mg/bid for chronic treatment.

Trial Locations (1)

602-715

Dong-A University Hospital, Busan

All Listed Sponsors
lead

Dong-A University

OTHER

NCT02944123 - Half Dose of Prasugrel and Ticagrelor in Acute Coronary Syndrome (HOPE-TAILOR) | Biotech Hunter | Biotech Hunter