NCT02939248View on ClinicalTrials.gov

Influence of Naloxone on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine

PHASE4CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 31, 2016

Primary Completion Date

December 31, 2018

Study Completion Date

December 31, 2018

Conditions
Unstable Angina Pectoris
Interventions
DRUG

Crushed ticagrelor followed by morphine

Crushed ticagrelor (180 mg) followed by morphine 5 mg intravenously

DRUG

Crushed ticagrelor, morphine,naloxone

Crushed ticagrelor (180 mg) orally followed by morphine 5 mg intravenously and naloxone 1 mg orally

Trial Locations (1)

85-094

Cardiology Department, Dr. A. Jurasz University Hospital, Bydgoszcz

All Listed Sponsors
lead

Collegium Medicum w Bydgoszczy

OTHER

NCT02939248 - Influence of Naloxone on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine | Biotech Hunter | Biotech Hunter