Influence of Metoclopramide on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine

PHASE4CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

July 31, 2016

Primary Completion Date

December 31, 2017

Study Completion Date

December 31, 2017

Conditions
Unstable Angina Pectoris
Interventions
DRUG

Crushed ticagrelor followed by morphine

Crushed ticagrelor (180 mg) followed by morphine 5 mg intravenously

DRUG

Crushed ticagrelor, morphine,metoclopramide

Crushed ticagrelor (180 mg) orally followed by morphine 5 mg and metoclopramide 10 mg intravenously

Trial Locations (1)

85-094

Cardiology Department, Dr. A. Jurasz University Hospital, Bydgoszcz

All Listed Sponsors
lead

Collegium Medicum w Bydgoszczy

OTHER

NCT02939235 - Influence of Metoclopramide on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine | Biotech Hunter | Biotech Hunter