NCT02939144View on ClinicalTrials.gov

An Investigation Into the Effect of Liquorice Ingestion on the Salivary Cortisol to Cortisone Molar Ratio

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

November 30, 2016

Primary Completion Date

March 6, 2017

Study Completion Date

March 6, 2017

Conditions
Apparent Mineralocorticoid Excess
Interventions
DIETARY_SUPPLEMENT

Liquorice

Liquorice ingestion will mimic the inherited condition of 'Apparent mineralocorticoid excess (AME)by showing the effects of the reduced activity of 11ßHSD-2 (which leads to an accumulation of cortisol which binds MR and hence has the effect of aldosterone).

Trial Locations (1)

WV10 0QP

The Royal Wolverhampton NHS Trust, Wolverhampton

All Listed Sponsors
lead

The Royal Wolverhampton Hospitals NHS Trust

OTHER_GOV

NCT02939144 - An Investigation Into the Effect of Liquorice Ingestion on the Salivary Cortisol to Cortisone Molar Ratio | Biotech Hunter | Biotech Hunter