IMPAACT 2002: Cognitive Behavioral Therapy and Medication Management for Treatment of Depression in US Youth With HIV

NACompletedINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

March 6, 2017

Primary Completion Date

September 12, 2019

Study Completion Date

January 21, 2020

Conditions
HIVDepression
Interventions
BEHAVIORAL

Health and Wellness Combined Cognitive Behavioral Therapy and a Medication Management Algorithm

Behavioral therapy based on a manualized approach developed specifically for youth living with both HIV and depression, using problem-solving, motivational interviewing and cognitive-behavioral strategies to decrease adherence obstacles and increase wellness. The medication management algorithm includes guidance for clinicians on strategies and tactics to treat depression in this population, including factors to consider when deciding on treatments (i.e., drug-drug interactions, side effects).

BEHAVIORAL

Enhanced Standard of Care

Ongoing psychopharmacological and psychosocial counseling and treatment for depression at HIV clinical treatment centers enhanced by providing clinicians with up-to-date information and didactic training on current principles for use of medication and psychotherapy in the treatment of depression.

Trial Locations (13)

10457

Bronx-Lebanon Hospital Center (CRS 5114), The Bronx

10461

Jacobi Medical Center (CRS 5013), The Bronx

11794

Stony Brook University Medical Center (CRS 5040), Stony Brook

21287

Johns Hopkins University School of Medicine (CRS 5092), Baltimore

30308

Emory University School of Medicine (CRS 5030), Atlanta

33316

Children's Diagnostic and Treatment Center (CRS 5055), Fort Lauderdale

38105

St Jude Children's Research Hospital (CRS 6501), Memphis

60612

Rush University Medical Center (CRS 5083), Chicago

77030

Texas Children's/Baylor (CRS 3801), Houston

80045

Children's Hospital of Colorado (CRS 5052), Aurora

90095

David Geffen School of Medicine at UCLA (CRS 5112), Los Angeles

91803

University of Southern California - MCA Center (CRS 5048),, Alhambra

92093

University California, San Diego (CRS 4601), La Jolla

All Listed Sponsors
collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

National Institute of Mental Health (NIMH)

NIH

lead

International Maternal Pediatric Adolescent AIDS Clinical Trials Group

NETWORK

NCT02939131 - IMPAACT 2002: Cognitive Behavioral Therapy and Medication Management for Treatment of Depression in US Youth With HIV | Biotech Hunter | Biotech Hunter