156
Participants
Start Date
March 6, 2017
Primary Completion Date
September 12, 2019
Study Completion Date
January 21, 2020
Health and Wellness Combined Cognitive Behavioral Therapy and a Medication Management Algorithm
Behavioral therapy based on a manualized approach developed specifically for youth living with both HIV and depression, using problem-solving, motivational interviewing and cognitive-behavioral strategies to decrease adherence obstacles and increase wellness. The medication management algorithm includes guidance for clinicians on strategies and tactics to treat depression in this population, including factors to consider when deciding on treatments (i.e., drug-drug interactions, side effects).
Enhanced Standard of Care
Ongoing psychopharmacological and psychosocial counseling and treatment for depression at HIV clinical treatment centers enhanced by providing clinicians with up-to-date information and didactic training on current principles for use of medication and psychotherapy in the treatment of depression.
Bronx-Lebanon Hospital Center (CRS 5114), The Bronx
Jacobi Medical Center (CRS 5013), The Bronx
Stony Brook University Medical Center (CRS 5040), Stony Brook
Johns Hopkins University School of Medicine (CRS 5092), Baltimore
Emory University School of Medicine (CRS 5030), Atlanta
Children's Diagnostic and Treatment Center (CRS 5055), Fort Lauderdale
St Jude Children's Research Hospital (CRS 6501), Memphis
Rush University Medical Center (CRS 5083), Chicago
Texas Children's/Baylor (CRS 3801), Houston
Children's Hospital of Colorado (CRS 5052), Aurora
David Geffen School of Medicine at UCLA (CRS 5112), Los Angeles
University of Southern California - MCA Center (CRS 5048),, Alhambra
University California, San Diego (CRS 4601), La Jolla
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
National Institute of Mental Health (NIMH)
NIH
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
NETWORK