Effect of Exercise on Endothelial Injury in Hypertensive Patients

NACompletedINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

December 31, 2019

Study Completion Date

January 31, 2020

Conditions
HypertensionHealthy
Interventions
OTHER

AEROBIC

The aerobic exercise session (AE) will consist of 40 minutes on an exercise bike in heart rate (HR) corresponding to 60% of heart rate reserve (moderate intensity) acquired by the formula of Karvonen: \[(HR max - HR rest) x desired intensity\] + HR rest; monitored through heart monitor brand Polar and perceived exertion rating (Borg scale of 6-20). It will be added to the exercise time 5-7 minutes to proper heating.

OTHER

RESISTANCE

The resistance exercise session (RE) will last 40 minutes and will consist in carrying out 4 sets of 12 repetitions with interval of 90 seconds between sets and exercises. The weight will be adjusted to 60 % of a maximum repetition (1-RM) (moderate intensity) in four exercise for the lower limbs: leg press, knee extension, bend knees and plantar flexion (calf). The cadence of each series will be controlled by electronic metronome and performed with 2 seconds in the concentric phase and 2 seconds in the eccentric phase. It will be added to the exercise time 5-7 minutes for the warming to be held in the leg press exercise (one set of 15 to 20 repetitions with 1/3 load set for the session).

OTHER

COMBINED

The combined exercise session (resistance and aerobic) will last 40 minutes. The exercise resistance phase of the combined session will consist of 20 minutes, according to the resistance exercise described above. Immediately after resistance exercise, patients will perform aerobic exercise (AE) for 20 minutes. In order to keep the equivalent time among the three interventions (aerobic exercise, resistance and combined) will be performed two series (2 x 12 repetitions) in each resistance exercise.

All Listed Sponsors
lead

Instituto de Cardiologia do Rio Grande do Sul

OTHER

NCT02937922 - Effect of Exercise on Endothelial Injury in Hypertensive Patients | Biotech Hunter | Biotech Hunter