Effect of Antimicrobial Treatment of Acute Otitis Media on the Intestinal Microbiome in Children

PHASE4CompletedINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

November 30, 2016

Primary Completion Date

March 31, 2020

Study Completion Date

March 31, 2020

Conditions
Acute Otitis Media
Interventions
DRUG

Amoxicillin

The children with acute otitis media will be treated with amoxixillin mixture, 100mg/ml, 40mg/kg/d, divided to two daily doses for 7 days.

DRUG

Amoxicillin-Potassium Clavulanate

The children with acute otitis media will be treated with amoxixillin-clavulanate mixture, 80mg/ml, 45mg/kg/d, divided to two daily doses for 7 days.

DRUG

Macrolide

The children with acute otitis media with a know allergy to amoxicillin or amoxicillin-clavulanate will be treated with macrolide and monitored separately

Trial Locations (1)

Unknown

Mehiläinen, private practice, Oulu

All Listed Sponsors
collaborator

Oulu University Hospital

OTHER

lead

University of Oulu

OTHER

NCT02935374 - Effect of Antimicrobial Treatment of Acute Otitis Media on the Intestinal Microbiome in Children | Biotech Hunter | Biotech Hunter