20
Participants
Start Date
October 14, 2016
Primary Completion Date
October 11, 2019
Study Completion Date
May 14, 2020
Lenvatinib
Pre-surgery Lenvatinib, days 1 - 5. Dose Escalation Levels: 1.) 10 mg by mouth (PO) daily (QD); 2.) 14 mg PO QD; 3.) 20 mg PO QD; 4.) 24 PO QD.
Capecitabine
Pre-surgery Capecitabine, 850 mg/m\^2, twice a day (BID) on days 1-5 for 5½ -6 weeks.
External Radiation Therapy (XRT)
Pre-surgery RT: Participants will receive 6 weeks of radiation therapy. The radiation sessions will be daily, Monday through Friday, except for holidays.
H. Lee Moffitt Cancer Center and Research Institute, Tampa
H. Lee Moffitt Cancer Center and Research Institute
OTHER