Multicentric Randomised Trial for Resectable Gastric Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

207

Participants

Timeline

Start Date

December 21, 2017

Primary Completion Date

April 30, 2025

Study Completion Date

March 31, 2029

Conditions
Gastric Cancer
Interventions
DRUG

Docetaxel

3 weekly course of docetaxel i.v in arm 1 and 2

DRUG

Oxaliplatin

3 weekly course oxaliplatin as a 2 hr i.v. in arm 1 and 2

DRUG

Capecitabine

oral capecitabine in arm 1 and 2

PROCEDURE

gastrectomy

resection of gastric cancer after pre-operative chemotherapy for all arms

RADIATION

radiotherapy of gastric cancer

5 weeks of radiation, 5 times a week with a total of 45 Gy (in arm 2 and 3)

DRUG

Paclitaxel

5 weeks of paclitaxel i.v once a week (in arm 2 and 3)

DRUG

Carboplatin

5 weeks of carboplatin i.v once a week (in arm 2 and 3)

Trial Locations (28)

6162 BG

Zuyderland Medisch Centrum, Sittard-Geleen

5912 BL

Viecuri Medisch Centrum, Venlo

5751 CB

Elkerliek, Deurne

5602 ZA

Catharina Ziekenhuis, Eindhoven

5631 BM

Maxima Medisch Centrum, Eindhoven

5664 EH

St. Anna Zorggroep, Geldrop

5707 HA

Elkerliek, Helmond

5022 GC

Instituut Verbeeten, Tilburg

5406 PT

Bernhoven, Uden

5504 DB

Maxima Medisch Centrum, Veldhoven

2000 AK

Spaarne Gasthuis, Hoofddorp

7609 PP

Ziekenhuisgroep Twente, Almelo

7416 SE

Deventer Ziekenhuis, Deventer

7512 KZ

Medisch Spectrum Twente, Enschede

8901BR

Medisch Centrum Leeuwarden, Leeuwarden

8934AD

Radiotherapeutisch Instituut Friesland, Leeuwarden

2625 AD

Reinier de Graaf Gasthuis, Delft

2333 ZA

Leids Universitair Medisch Centrum, Leiden

5223 GZ

Jeroen Bosch Ziekenhuis, 's-Hertogenbosch

1066CX

Netherlands Cancer Instituut, Amsterdam

1105AZ

Academisch Medisch Centrum, Amsterdam

6815AD

Rijnstate, Arnhem

6716RP

Ziekenhuis Gelderse Vallei, Ede

9713 GZ

Universitair Medisch Centrum Groningen, Groningen

3435CM

Ziekenhuis St Antonius, Nieuwegein

2545AA

HAGA ziekenhuis, The Hague

5022GC

Elisabeth Tweesteden Ziekenhuis, Tilburg

3508 GA

Universitair Medisch Centrum Utrecht, Utrecht

All Listed Sponsors
lead

The Netherlands Cancer Institute

OTHER