NCT02928510 - Mechanisms of Idelalisib-Associated Diarrhea in Patients With Relapsed Chronic Lymphocytic Leukemia, Indolent Non-hodgkin Lymphoma, or Small Lymphocytic Lymphoma | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

February 1, 2016

Primary Completion Date

June 5, 2018

Study Completion Date

June 5, 2018

Conditions

Absence of Signs or SymptomsB-Cell Non-Hodgkin LymphomaDigestive System Signs and SymptomsIndolent Adult Non-Hodgkin LymphomaRecurrent B-Cell Non-Hodgkin LymphomaRecurrent Chronic Lymphocytic LeukemiaRecurrent Indolent Adult Non-Hodgkin LymphomaRecurrent Small Lymphocytic Lymphoma

Interventions

PROCEDURE

Biospecimen Collection

Undergo biospecimen collection

PROCEDURE

Colonoscopy

Undergo colonoscopy

PROCEDURE

Colposcopic Biopsy

Undergo colposcopic biopsy

DRUG

Idelalisib

Given PO

OTHER

Laboratory Biomarker Analysis

Correlative studies

OTHER

Pharmacological Study

Correlative studies

PROCEDURE

Physical Examination

Undergo physical examination

PROCEDURE

Sigmoidoscopy

Undergo sigmoidoscopy

Trial Locations (1)

90095

UCLA / Jonsson Comprehensive Cancer Center, Los Angeles