A Study of Nivolumab Plus Brentuximab Vedotin in Patients Between 5 and 30 Years Old, With Hodgkin's Lymphoma (cHL), Relapsed or Refractory From First Line Treatment

PHASE2CompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

March 28, 2017

Primary Completion Date

May 28, 2024

Study Completion Date

May 28, 2024

Conditions
Hodgkin Disease
Interventions
BIOLOGICAL

Nivolumab

Specified Dose on Specified Days

BIOLOGICAL

brentuximab vedotin

Specified Dose on Specified Days

BIOLOGICAL

bendamustine

Specified Dose on Specified Days

Trial Locations (79)

13011

Local Institution - 0032, Marseille

13353

Local Institution - 0056, Berlin

14263

Local Institution - 0068, Buffalo

15224

Childrens Hospital Of Pittsburgh Of Upmc, Pittsburgh

16147

Local Institution - 0021, Genova

19104

Childrens Hospital Of Philadelphia, Philadelphia

19803

Nemours / A. I. duPont Hospital for Children, Wilmington

20010

Children'S National Medical Center, Washington D.C.

20900

Local Institution - 0019, Monza (mb)

21287

Local Institution - 0070, Baltimore

23219

Virginia Commonwealth University, Richmond

27599

Local Institution, Chapel Hill

28009

Local Institution - 0084, Madrid

28203

Carolinas Medical Center, Charlotte

30322

Children's Healthcare Of Atlanta, Atlanta

30625

Local Institution - 0057, Hanover

31059

Local Institution - 0033, Toulouse

32207

Local Institution - 0062, Jacksonville

33081

Local Institution - 0024, Aviano (PN)

33701

Local Institution - 0069, St. Petersburg

35233

Children's Hospital of Alabama, Birmingham

35392

Local Institution - 0055, Giessen

39216

Local Institution - 0049, Jackson

40138

Local Institution - 0020, Bologna

43205

Local Institution - 0089, Columbus

44093

Local Institution - 0028, Nantes

48201

Local Institution - 0097, Detroit

52242

University Of Iowa, Iowa City

53226

Local Institution - 0065, Milwaukee

54511

Local Institution - 0034, Vandœuvre-lès-Nancy

59037

Local Institution - 0030, Lille

63110

Washington University School Of Medicine, St Louis

64108

Local Institution - 0085, Kansas City

69008

Local Institution - 0029, Lyon

73104

University Of Oklahoma Health Sciences Center, Oklahoma City

75012

Local Institution - 0031, Paris

75019

Local Institution - 0026, Paris

75235

Local Institution - 0071, Dallas

77030

Baylor College Of Medicine, Houston

78723

Local Institution - 0042, Austin

80045

Childrens Hospital of Colorado, Aurora

80123

Local Institution - 0023, Napoli

80337

Local Institution - 0102, München

84113

Primary Children's Hospital, Salt Lake City

85016

Phoenix Children'S Hospital, Phoenix

89135

Nevada Cancer Research Foundation, Las Vegas

92109

Local Institution - 0091, San Diego

92350

Loma Linda University Cancer Center, Loma Linda

92868

Children'S Hospital Of Orange County, Orange

93636

Valley Children's Hospital, Madera

94304

Lucile Packard Children'S Research Hospital/Stanford Univ, Palo Alto

94609

Children'S Hospital & Research Center At Oakland, Oakland

94805

Local Institution - 0027, Villejuif

98105

Local Institution - 0048, Seattle

06520

Smilow Cancer Hospital At Yale New Haven Hospital, New Haven

02215

Dana Farber Cancer Institute., Boston

07601

Local Institution - 0067, Hackensack

08903

Local Institution - 0047, New Brunswick

45229-3039

Cincinnati Children'S Hospital Medical Center, Cincinnati

17033-0850

Local Institution - 0090, Hershey

37232-6310

Vanderbilt University, Nashville

23507-1910

Children'S Hosp-Kings Daughter, Norfolk

T3B 6A8

Local Institution, Calgary

M5G 1X8

Local Institution - 0092, Toronto

H4A 3J1

The Montreal Children's Hospital of the MUHC, Montreal

150 06

Klinika detske hematologie a onkologie, Prague

Dublin 8

Local Institution - 0017, Dublin

00161

Local Institution - 0022, Roma

3015 CN

Local Institution - 0001, Rotterdam

3584 CS

Local Institution - 0006, Utrecht

80-952

Local Institution, Gdansk

30-663

Local Institution, Krakow

08950

Local Institution - 0082, Barcelona

LS1 3EX

Local Institution - 0035, Leeds

LS9 7TF

Local Institution, Leeds

B15 2TH

Local Institution, Birmingham

G51 4TF

Local Institution, Glasgow

NW1 2BU

Local Institution - 0002, London

M13 9WL

Local Institution - 0012, Manchester

Sponsors
All Listed Sponsors
collaborator

Seagen Inc.

INDUSTRY

lead

Bristol-Myers Squibb

INDUSTRY