Real-Time Assessment Of Breast Cancer Lumpectomy Specimen Margins With Nonlinear Microscopy

NARecruitingINTERVENTIONAL
Enrollment

98

Participants

Timeline

Start Date

July 17, 2019

Primary Completion Date

August 31, 2024

Study Completion Date

August 31, 2025

Conditions
Breast Cancer
Interventions
DEVICE

nonlinear microscopy imaging of excised surgical margins

Following standard lumpectomy excision, excised tissue will be imaged with NLM. If invasive cancer or ductal carcinoma in situ (DCIS) is detected on or close to the margin, additional excision may be performed. Following surgery, final margins will be evaluated using paraffin embedded histopathology as per standard procedure. Paraffin embedded histopathology will be used to make a final margin determination.

PROCEDURE

standard lumpectomy without nonlinear microscopy imaging

Lumpectomy with postoperative paraffin embedded histopathology to make a final margin determination.

Trial Locations (1)

02115

RECRUITING

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
collaborator

Massachusetts Institute of Technology

OTHER

collaborator

Dana-Farber Cancer Institute

OTHER

lead

Beth Israel Deaconess Medical Center

OTHER