Crushed Ticagrelor Versus Eptifibatide Bolus + Clopidogrel

PHASE2CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

November 1, 2016

Primary Completion Date

January 30, 2018

Study Completion Date

December 1, 2018

Conditions
Acute Coronary SyndromeAngina, Unstable
Interventions
DRUG

Ticagrelor

After randomization, a blood sample will be obtained at baseline for platelet function study, the study drugs, crushed ticagrelor will be administered. Patients will undergo PCI using drug-eluting stents or bare-metal stents. Blood samples will be obtained at 30 mins, 2, 4, and 24 h after PCI for platelet function tests.

DRUG

Eptifibatide

After randomization, a blood sample will be obtained at baseline for platelet function test, the study drugs, clopidogrel and eptifibatide bolus will be administered. Patients will undergo PCI using drug-eluting stents or bare-metal stents. Blood samples will be obtained at 30 mins, 2, 4, and 24 h after PCI for platelet function tests.

DRUG

Clopidogrel

Trial Locations (1)

35294

University of Alabama, Birmingham

All Listed Sponsors
lead

University of Alabama at Birmingham

OTHER

NCT02925923 - Crushed Ticagrelor Versus Eptifibatide Bolus + Clopidogrel | Biotech Hunter | Biotech Hunter