NCT02922894View on ClinicalTrials.gov

Treatment of Sleep Apnea in Patients with Cervical Spinal Cord Injury

PHASE4RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 9, 2017

Primary Completion Date

January 31, 2026

Study Completion Date

June 30, 2026

Conditions
Sleep ApneaSpinal Cord Injury
Interventions
PROCEDURE

Acute episodic hypoxia

The subjects will undergo 30 minutes of baseline monitoring followed by 15 episodes of one minute of episodic hypoxia with supplemental CO2 to maintain isocapnia. This is followed by a 45 minute recovery period.

PROCEDURE

Supplemental oxygen

Supplemental oxygen therapy for 6 weeks

DRUG

Trazodone

100mg before bedtime

DRUG

Placebo

One placebo pill before-bedtime

PROCEDURE

Sham

Room air will be administered instead of episodic hypoxia or supplemental oxygen..

Trial Locations (1)

48201

RECRUITING

John D. Dingell VA Medical Center, Detroit

All Listed Sponsors
collaborator

United States Department of Defense

FED

lead

John D. Dingell VA Medical Center

FED