45
Participants
Start Date
February 14, 2017
Primary Completion Date
March 30, 2019
Study Completion Date
August 28, 2024
Tracer-enhanced oral glucose tolerance test (OGTT*)
Oral glucose tolerance test with stable isotope tracers will be administered. Resting energy expenditure and respiratory quotient will be evaluated during this test using indirect calorimetry.
Muscle MRI
Non-invasive muscle MRI will be performed to evaluated metabolic capacity.
Dual energy x-ray absorptiometry (DXA)
DXA will be performed to evaluate body composition.
Questionnaires
Questionnaires will be used to evaluate participants' health and habits.
University of Pennsylvania, Philadelphia
Children's Hospital of Philadelphia, Philadelphia
University of Pennsylvania
OTHER