A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine

PHASE3CompletedINTERVENTIONAL
Enrollment

178

Participants

Timeline

Start Date

November 30, 2016

Primary Completion Date

July 31, 2020

Study Completion Date

July 31, 2020

Conditions
MetastasisBreast Cancer
Interventions
DRUG

NKTR-102

DRUG

Eribulin

DRUG

Ixabepilone

DRUG

Vinorelbine

DRUG

Gemcitabine

DRUG

Paclitaxel

DRUG

Docetaxel

DRUG

Nab-paclitaxel

Trial Locations (56)

144

Investigator Site - Roma, Roma

1000

Investigator Site - Brussels, Brussels

1180

Investigator Site - Brussels, Brussels

1200

Investigator Site - Brussels, Brussels

Investigator Site - Woluwe- Saint-Lambert, Woluwe-Saint-Lambert

2010

Investigator Site - Darlinghurst, Darlinghurst

2500

Investigator Site - Wollongong, Wollongong

2640

Investigatory Site - Albury, Albury

2650

Investigator Site - Edegem, Edegem

3128

Investigator Site - Box Hill, Box Hill

4000

Investigator Site - Liege, Liège

6000

Investigator Site - Charleroi, Charleroi

6008

Investigator Site - Subiaco, Subiaco

6009

Investigator Site - Nedlands, Nedlands

8023

Investigator Site - Barcelona, Barcelona

8035

Investigator Site - Barcelona, Barcelona

10065

Investigator Site - New York, New York

20132

Investigator Site - Milan, Milan

20141

Investigator Site - Milano, Milan

21201

Investigator Site - Baltimore, Baltimore

27599

Investigator Site - Chapel Hill, Chapel Hill

28040

Investigator Site - Madrid, Madrid

30029

Investigator Site - Nimes, Nîmes

30607

Investigator Site - Athens, Athens

31096

Investigator Site - Haifa, Haifa

33136

Investigator Site - Miami, Miami

33324

Investigator Site - Plantation, Plantation

33401

Investigator Site - West Palm Beach, West Palm Beach

35042

Investigator Site - Rennes, Rennes

38138

Investigator Site - Germantown, Germantown

38320

Investigator Site - Santa Cruz de Tenerife, Santa Cruz de Tenerife

41013

Investigator Site - Sevilla, Seville

43210

Investigator Site - Columbus, Columbus

55455

Investigator Site - Minneapolis, Minneapolis

63110

Investigator Site - Saint Louis, St Louis

64239

Investigator Site - Tel Aviv, Tel Aviv

67091

Investigator Site - Strasbourg, Strasbourg

72000

Investigator Site - Le Mans, Le Mans

75248

Investigator Site - Paris, Paris

76038

Investigator Site - Rouen, Rouen

76104

Investigator Site - Fort Worth, Fort Worth

77030

Investigator Site - Houston, Houston

80131

Investigator Site - Napoli, Napoli

84101

Investigator Site - Beersheba, Beersheba

84106

Investigator Site - Salt Lake City, Salt Lake City

85724

Investigator Site - Tucson, Tucson

92868

Investigator Site - Orange, Orange

94115

Investigator Site - San Francisco, San Francisco

98109

Investigator Site - Seattle, Seattle

02115

Investigator Site - Boston, Boston

H4A 3J1

Investigator Site - Montreal, Montreal

1649-035

Investigator Site - Lisboa, Lisbon

4200-072

Investigator Site - Porto, Porto

BD7 1DP

Investigator Site - Bradford, Bradford

M20 4BX

Investigator Site - Manchester, Manchester

NG5 1PB

Investigator Site - Nottingham, Nottingham

Sponsors
All Listed Sponsors
lead

Nektar Therapeutics

INDUSTRY