NCT02909478View on ClinicalTrials.gov

Aprepitant Without Steroid in Preventing Chemotherapy-induced Nausea and Vomiting in Patients With Colorectal Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

315

Participants

Timeline

Start Date

September 1, 2017

Primary Completion Date

October 23, 2019

Study Completion Date

December 31, 2019

Conditions
Chemotherapy-induced Nausea and VomitingColorectal Cancer
Interventions
DRUG

Aprepitant+Tropisetron

"Patients will receive the chemotherapy drugs oxaliplatin,leucovorin and 5-fluorouracil as well as the following antiemetic drugs:~aprepitant (125 mg orally on day 1 and 80 mg orally on days 2 and 3) plus Tropisetron (5mg IV of day1)"

DRUG

Dexamethasone+Tropisetron

"Patients will receive the chemotherapy drugs oxaliplatin, leucovorin and 5-fluorouracil as well as the following antiemetic drugs:~Dexamethasone (10 mg IV on day 1 and 5 mg IV days 2, 3) plus Tropisetron (5mg IV of day1)"

Trial Locations (1)

510655

Gastrointestinal Hospital, Sun Yat-sen University, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER

NCT02909478 - Aprepitant Without Steroid in Preventing Chemotherapy-induced Nausea and Vomiting in Patients With Colorectal Cancer | Biotech Hunter | Biotech Hunter