NCT02908308 - Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest | Biotech Hunter

Enrollment

1,900

Participants

Timeline

Start Date

November 18, 2017

Primary Completion Date

June 30, 2022

Study Completion Date

December 31, 2022

Conditions

Out-of-hospital Cardiac Arrest

Interventions

PROCEDURE

Targeted temperature management to 33°C

Rapid cooling to below 33°C, followed by temperature control at 33°C for up to 28h.

PROCEDURE

Standard care with early treatment of fever

Normothermia and standard care - use of a device for temperature control if temperature is greater than or equal to 37.8°C

Trial Locations (60)

6021

Wellington Hospital, Wellington

15213

UPMC-Presbyterian, Pittsburgh

22185

Skane University Hospital - Lund, Lund

Skane University Hospital - Malmö, Malmo

55905

Mayo Clinic Hospital-St. Mary's Campus, Rochester

Unknown

John Hunter Hospital, Newcastle

Concord Repatriation General Hospital, Sydney

Liverpool Hospital, Sydney

St Vincent's Hospital, Sydney

Princess Alexandra Hospital, Brisbane

Northern Hospital, Epping

The Alfred, Melbourne

Austin Hospital, Melbourne

Nepean Hospital, Sydney

Royal North Shore Hospital, Sydney

Innsbruck University Hospital, Innsbruck

Erasme Hospital, Brussels

Ziekenhuis Oost-Limburg, Genk

Hradec Kralove Hospital, Hradec Králové

Liberec Hospital, Liberec

General University Hospital, Prague

Aarhus University Hospital, Aarhus

Chu Dupuytren, Limoges

CHU Nantes, Nantes

Cochin University Hospital, Paris

Lariboisière Hospital, Paris

Versailles Hospital, Versailles

Charité, Campus Virchow, Berlin

San Martino Hospital, Genova

Modena NOCSAE Hospital, Modena

Christchurch Hospital, Christchurch

Sorlandet Hospital, Arendal

Haukeland Hospital, Bergen

Oslo University Hospital, Oslo

St. Olav's University Hospital, Trondheim

Sahlgrenska University Hospital, Gothenburg

Linköping University Hospital, Linköping

Örebro University Hospital, Örebro

Skaraborgs sjukhus, Skövde

Capio St:Göran, Stockholm

Södersjukhuset, Stockholm

Akademiska Sjukhuset, Uppsala

University Hospital Bern, Inselspital, Bern

University Hospital of Lausanne, Lausanne

Cardiocentro Ticino, Lugano

Kantonsspital St.Gallen, Sankt Gallen

Zurich University Hospital, Zurich

Basildon and Thurrock Hospitals NHS Foundation Trust - Essex CTC, Basildon

Royal Victoria Hospital, Belfast

Birmingham University Hospital, Birmingham

Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust, Bournemouth

Bristol Royal Infirmary, Bristol

University Hospital of Wales, Cardiff

Manchester Royal Infirmary, Manchester

Queen Alexandra Hospital, Portsmouth

Royal Berkshire Hospital, Reading

302 33

Hallands Hospital, Halmstad

251 87

Helsingborgs Hospital, Helsingborg

652 30

Centralsjukhuset i Karlstad, Karlstad

461 73

Norra Älvsborgs Länssjukhus (NÄL), Trollhättan