3
Participants
Start Date
October 12, 2017
Primary Completion Date
March 4, 2022
Study Completion Date
March 4, 2022
Methotrexate
Methotrexate 4 mg into fourth ventricle of the brain via the Ommaya Reservoir 2 days a week for 6 weeks. Each patient will have 12 infusions.
Etoposide
Etoposide 1 mg into fourth ventricle of the brain via the Ommaya Reservoir 5 days a week for weeks 1, 3, and 5. Each patient will have 15 infusions.
Ommaya Reservoir
Surgical catheter placement into the fourth ventricle of the brain
UTHealth & Children's Memorial Hermann Hospital, Houston
The University of Texas Health Science Center, Houston
OTHER