Stem Cell Therapy for Outer Retinal Degenerations

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

August 31, 2015

Primary Completion Date

January 31, 2019

Study Completion Date

June 30, 2019

Conditions
Age Related Macular DegenerationStargardt's DiseaseExudative Age-related Macular Degeneration
Interventions
PROCEDURE

injection of hESC-RPE in suspension

The first six patients will receive a sub retinal injection of hESC-RPE in solution after a complete pars plana vitrectomy to access safety of the cell implant alone.

PROCEDURE

injection hESC-RPE seeded in a substrate

Fifteen patients will receive a sub-retinal implantation of embryonic stem cell derived retinal pigmented epithelium seeded in a polymeric substrate to access safety of substrate seeded with RPE

Trial Locations (1)

04023-062

Federal University of Sao Paulo, São Paulo

All Listed Sponsors
lead

Federal University of São Paulo

OTHER

NCT02903576 - Stem Cell Therapy for Outer Retinal Degenerations | Biotech Hunter | Biotech Hunter