81
Participants
Start Date
September 21, 2017
Primary Completion Date
January 4, 2022
Study Completion Date
January 4, 2022
Zonisamide
ZONEGRAN® (zonisamide) is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. A dose of 400 mg daily will be used as the target maintenance dose in this study but dosing will be modified if needed to adjust for subject tolerance of drug dosing.
Take Control
"Take Control is a seven module computer-based intervention which presents evidence-based alcohol education that includes motivational interviewing and cognitive-behavioral skills building. This program is derived from the National Institute on Alcohol Abuse and Alcoholism's (NIAAA's) self-help approach, Rethinking Drinking.~Starting on March 23, 2020, participants will participate in a simplified Take Control treatment at home due to the COVID-19 pandemic"
Placebo (for Zonisamide)
Sugar pills manufactured to mimic Zonisamide capsules.
Center for Anxiety and Related Disorders - Boston University, Boston
Mclean Hospital
OTHER
University of Houston
OTHER
Boston University Charles River Campus
OTHER