Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism

PHASE3CompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

September 21, 2017

Primary Completion Date

January 4, 2022

Study Completion Date

January 4, 2022

Conditions
Alcohol Dependence
Interventions
DRUG

Zonisamide

ZONEGRAN® (zonisamide) is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. A dose of 400 mg daily will be used as the target maintenance dose in this study but dosing will be modified if needed to adjust for subject tolerance of drug dosing.

BEHAVIORAL

Take Control

"Take Control is a seven module computer-based intervention which presents evidence-based alcohol education that includes motivational interviewing and cognitive-behavioral skills building. This program is derived from the National Institute on Alcohol Abuse and Alcoholism's (NIAAA's) self-help approach, Rethinking Drinking.~Starting on March 23, 2020, participants will participate in a simplified Take Control treatment at home due to the COVID-19 pandemic"

DRUG

Placebo (for Zonisamide)

Sugar pills manufactured to mimic Zonisamide capsules.

Trial Locations (1)

02115

Center for Anxiety and Related Disorders - Boston University, Boston

All Listed Sponsors
collaborator

Mclean Hospital

OTHER

collaborator

University of Houston

OTHER

lead

Boston University Charles River Campus

OTHER

NCT02901041 - Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism | Biotech Hunter | Biotech Hunter