NCT02900378 - randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure | Biotech Hunter

Enrollment

621

Participants

Timeline

Start Date

December 20, 2016

Primary Completion Date

April 11, 2018

Study Completion Date

April 11, 2018

Conditions

Chronic Heart Failure With Reduced Ejection Fraction

Interventions

DRUG

LCZ696 (Sacubitril/Valsartan)

LCZ696 (sacubitril/valsartan) was available in 24 mg/26 mg, 49 mg/51 and 97 mg/103 mg mg film-coated tablets

DRUG

Placebo of LCZ696 (Sacubitril/Valsartan)

Placebo of LCZ696 (sacubitril/valsartan) was available to match 24 mg/26 mg, 49 mg/51 and 97 mg/103 mg mg film-coated tablets

DRUG

Enalapril

Enalapril was available in 2.5 mg, 5 mg and 10 mg film-coated tablets

DRUG

Placebo of Enalapril

Placebo of Enalapril was available to match 2.5 mg, 5 mg and 10 mg film-coated tablets

Trial Locations (119)

201

Novartis Investigative Site, Kopavogur

1012

Novartis Investigative Site, Riga

1233

Novartis Investigative Site, Sofia

1606

Novartis Investigative Site, Sofia

1709

Novartis Investigative Site, Sofia

2093

Novartis Investigative Site, Feiring

2300

Novartis Investigative Site, Turnhout

2440

Novartis Investigative Site, Geel

2650

Novartis Investigative Site, Edegem

3001

Novartis Investigative Site, Jelgava

4000

Novartis Investigative Site, Plovdiv

Novartis Investigative Site, Roskilde

5001

Novartis Investigative Site, Ogre

5700

Novartis Investigative Site, Svendborg

5800

Novartis Investigative Site, Pleven

6419

Novartis Investigative Site, Heerlen

8930

Novartis Investigative Site, Randers

9000

Novartis Investigative Site, Ghent

9200

Novartis Investigative Site, Dendermonde

10003

Novartis Investigative Site, Cáceres

10138

Novartis Investigative Site, Tallinn

10787

Novartis Investigative Site, Berlin

10789

Novartis Investigative Site, Berlin

11540

Novartis Investigative Site, Sanlúcar de Barrameda

11650

Novartis Investigative Site, Villamartín

13055

Novartis Investigative Site, Berlin

13100

Novartis Investigative Site, Hämeenlinna

13353

Novartis Investigative Site, Berlin

13419

Novartis Investigative Site, Tallinn

14004

Novartis Investigative Site, Córdoba

15405

Novartis Investigative Site, Ferrol

15706

Novartis Investigative Site, Santiago de Compostela

17007

Novartis Investigative Site, Girona

17176

Novartis Investigative Site, Stockholm

18014

Novartis Investigative Site, Granada

21005

Novartis Investigative Site, Huelva

21244

Novartis Investigative Site, Buchholz in der Nordheide

22041

Novartis Investigative Site, Hamburg

22880

Novartis Investigative Site, Wedel

23858

Novartis Investigative Site, Reinfeld

24071

Novartis Investigative Site, León

27003

Novartis Investigative Site, Lugo

28031

Novartis Investigative Site, Madrid

28222

Novartis Investigative Site, Madrid

32584

Novartis Investigative Site, Löhne

33011

Novartis Investigative Site, Oviedo

33290

Novartis Investigative Site, Gijón

33520

Novartis Investigative Site, Tampere

38820

Novartis Investigative Site, Halberstadt

39008

Novartis Investigative Site, Santander

41009

Novartis Investigative Site, Seville

42005

Novartis Investigative Site, Soria

43001

Novartis Investigative Site, Chomutov

45355

Novartis Investigative Site, Essen

46940

Novartis Investigative Site, Manises

51014

Novartis Investigative Site, Tartu

60200

Novartis Investigative Site, Brno

60594

Novartis Investigative Site, Frankfurt

61348

Novartis Investigative Site, Bad Homburg

63003

Novartis Investigative Site, Clermont-Ferrand

63128

Novartis Investigative Site, Dietzenbach

67454

Novartis Investigative Site, Haßloch

68165

Novartis Investigative Site, Mannheim

74370

Novartis Investigative Site, Metz-Tessy

74523

Novartis Investigative Site, Schwäbisch Hall

84453

Novartis Investigative Site, Mühldorf

89000

Novartis Investigative Site, Auxerre

90402

Novartis Investigative Site, Nuremberg

91425

Novartis Investigative Site, Lodz

94574

Novartis Investigative Site, Wallerfing

568 25

Novartis Investigative Site, Svitavy

434 01

Novartis Investigative Site, Most

280 20

Novartis Investigative Site, Kolín

106 00

Novartis Investigative Site, Prague

150 00

Novartis Investigative Site, Prague

DK-3000

Novartis Investigative Site, Elsinore

DK 5000

Novartis Investigative Site, Odense C

01099

Novartis Investigative Site, Dresden

04910

Novartis Investigative Site, Elsterwerda

04103

Novartis Investigative Site, Leipzig

57 072

Novartis Investigative Site, Siegen

04779

Novartis Investigative Site, Wermsdorf

681 00

Novartis Investigative Site, Alexandroupoli

711 10

Novartis Investigative Site, Heraklion Crete

166 73

Novartis Investigative Site, Voula

115 27

Novartis Investigative Site, Athens

151 27

Novartis Investigative Site, Athens

IS-101

Novartis Investigative Site, Reykjavik

Unknown

Novartis Investigative Site, Dublin

LV 1002

Novartis Investigative Site, Riga

LV-1001

Novartis Investigative Site, Riga

LT 50161

Novartis Investigative Site, Kaunas

LT-92288

Novartis Investigative Site, Klaipėda

LT-08661

Novartis Investigative Site, Vilnius

4462 RA

Novartis Investigative Site, Goes

2035 RC

Novartis Investigative Site, Haarlem

2353 GA

Novartis Investigative Site, Leiderdorp

6043 CV

Novartis Investigative Site, Roermond

5504 DB

Novartis Investigative Site, Veldhoven

02-676

Novartis Investigative Site, Warsaw

02-097

Novartis Investigative Site, Warsaw

02-507

Novartis Investigative Site, Warsaw

05077

Novartis Investigative Site, Warsaw

03293

Novartis Investigative Site, Elche

09400

Novartis Investigative Site, Aranda de Duero

09006

Novartis Investigative Site, Burgos

08208

Novartis Investigative Site, Sabadell

03010

Novartis Investigative Site, Alicante

08041

Novartis Investigative Site, Barcelona

222 21

Novartis Investigative Site, Lund

431 80

Novartis Investigative Site, Mölndal

TS19 8PE

Novartis Investigative Site, Stockton-on-Tees

NN14 6JQ

Novartis Investigative Site, Rothwell

SN7 7YU

Novartis Investigative Site, Faringdon

NE9 6SX

Novartis Investigative Site, Gateshead

BH7 7DW

Novartis Investigative Site, Bournemouth

CA139HT

Novartis Investigative Site, Cumbria

BH15 2JB

Novartis Investigative Site, Poole

NN8 4RW

Novartis Investigative Site, Wellingborough