NCT02898779View on ClinicalTrials.gov

Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1

PHASE1CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

May 1, 2017

Primary Completion Date

March 1, 2018

Study Completion Date

March 1, 2018

Conditions
Malaria
Interventions
DRUG

Primaquine, R-Primaquine, S-Primaquine, SR Primaquine

"Cohort 1: Eighteen individuals (6 per group) Cohort 2: Eighteen individuals (6 per group)~Group 1-15 mg of S-Primaquine followed by one-week washout, 15 mg of R-Primaquine followed by one week washout, and 30 mg of RS-Primaquine.~Group 2- 15 mg of R-Primaquine followed by one-week washout, 30 mg of RSPQ followed by one week washout, and 15 mg of SPQ.~Group 3- 30 mg of RS-Primaquine followed by one week washout,15 mg of SPQ followed by a one week washout, and 15 mg of RPQ."

Trial Locations (1)

38677

University of Mississippi, Oxford

All Listed Sponsors
lead

University of Mississippi, Oxford

OTHER

NCT02898779 - Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1 | Biotech Hunter | Biotech Hunter