Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

PHASE1RecruitingINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

September 30, 2016

Primary Completion Date

September 30, 2026

Study Completion Date

December 31, 2026

Conditions
Autonomic FailurePure Autonomic FailureMultiple System AtrophyParkinson DiseaseOrthostatic Hypotension
Interventions
DRUG

Droxidopa

Single oral dose 300 mg

DRUG

Midodrine

Single oral dose 10 mg

DRUG

Placebo

sugar pill

Trial Locations (1)

37232

RECRUITING

Autonomic Dysfunction Center/ Vanderbilt University Medical Center, Nashville

All Listed Sponsors
lead

Vanderbilt University Medical Center

OTHER