Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in Children

PHASE4CompletedINTERVENTIONAL
Enrollment

385

Participants

Timeline

Start Date

December 2, 2016

Primary Completion Date

December 16, 2019

Study Completion Date

December 16, 2019

Conditions
Pneumonia
Interventions
DRUG

Amoxicillin

Amoxicillin is an aminopenicillin antibiotic

DRUG

Amoxicillin-clavulanate

A fixed-ratio combination of amoxicillin trihydrate, an aminopenicillin, and potassium clavulanate, a beta-lactamase inhibitor, used to treat a broad-spectrum of bacterial infections, especially resistant strains.

DRUG

Cefdinir

Cefdinir is a cephalosporin antibiotic used to treat bacterial infections in many different parts of the body.

OTHER

Placebo

Placebo

Trial Locations (9)

27704

Duke Human Vaccine Institute - Duke Vaccine and Trials Unit, Durham

40202

University of Louisville School of Medicine - Norton Children's Hospital - Infectious Diseases, Louisville

35233-1711

University of Alabama - Children's of Alabama - Infectious Diseases/Virology, Birmingham

72202-3500

Arkansas Children's Hospital - Infectious Diseases, Little Rock

63110-1010

Washington University School of Medicine in St. Louis - Infectious Diseases, St Louis

45229-3039

Cincinnati Children's Hospital Medical Center - Infectious Diseases, Cincinnati

19104-3309

Children's Hospital of Philadelphia - The Center for Pediatric Clinical Effectiveness, Philadelphia

15213-3205

Children's Hospital of Pittsburgh of UPMC - General Academic Pediatric, Pittsburgh

37232-2573

Vanderbilt University - Pediatric - Vanderbilt Vaccine Research Center, Nashville

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT02891915 - Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in Children | Biotech Hunter | Biotech Hunter