4-drug Nerve Block Versus Plain Local Anesthetic for Knee and Hip Arthroplasty Analgesia in Veterans

PHASE3CompletedINTERVENTIONAL
Enrollment

98

Participants

Timeline

Start Date

October 31, 2016

Primary Completion Date

July 12, 2021

Study Completion Date

August 20, 2021

Conditions
Pain
Interventions
DRUG

Bupivacaine + CBD (clonidine, buprenorphine, dexamethasone)

Nerve blocks before surgery of L2-L4 and L4-S3 for Knee replacements Nerve blocks before surgery of L2-L4 for hip replacements

DRUG

Bupivacaine Only (control arm)

Nerve blocks before surgery of L2-L4 and L4-S3 for Knee replacements Nerve blocks before surgery of L2-L4 for hip replacements

Trial Locations (1)

15240

VA Pittsburgh Healthcare System, Pittsburgh

All Listed Sponsors
collaborator

University of Pittsburgh

OTHER

lead

Brian Williams

FED

NCT02891798 - 4-drug Nerve Block Versus Plain Local Anesthetic for Knee and Hip Arthroplasty Analgesia in Veterans | Biotech Hunter | Biotech Hunter