NCT02881086View on ClinicalTrials.gov

Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment

PHASE3CompletedINTERVENTIONAL
Enrollment

1,000

Participants

Timeline

Start Date

August 31, 2016

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Acute Lymphoblastic LeukemiaLymphoblastic Lymphoma
Interventions
DRUG

Rituximab

DRUG

Nelarabine

DRUG

PEG-Asparaginase

PROCEDURE

Cranial irradiation

DRUG

Imatinib

DRUG

Idarubicin

DRUG

Dexamethasone

DRUG

Cyclophosphamide

DRUG

Fludarabine

DRUG

Vincristine

DRUG

Mercaptopurine

DRUG

VP16

DRUG

Daunorubicin (DNR)

DRUG

Methotrexate

PROCEDURE

Stem cell transplantation

DRUG

Cytarabine

DRUG

Vindesine

DRUG

Adriamycin

DRUG

Prednisolone

Trial Locations (1)

60590

University Hospital of Frankfurt (Main), Frankfurt am Main

Sponsors

Lead Sponsor

Goethe University
All Listed Sponsors
lead

Goethe University

OTHER