Is There Any Correlation Between Plasmatic Zonulin and Expression of Intestinal Tight Junction Proteins in IBS Patients?

NACompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

February 2, 2017

Primary Completion Date

May 20, 2021

Study Completion Date

May 20, 2021

Conditions
Irritable Bowel Syndrome
Interventions
PROCEDURE

colonoscopy with biopsies in the left colon to assess intestinal permeability

"Eleven colonic biopsies are taken in the left colon during colonoscopy. Intestinal permeability is assessed by western blot, qPCR and immunofluorescence for claudin; occludin and ZO-1.~One blood sample is taken to assess plasmatic zonulin (ELISA kit)."

Trial Locations (1)

76031

Rouen University Hospital, Rouen

All Listed Sponsors
lead

University Hospital, Rouen

OTHER

NCT02877654 - Is There Any Correlation Between Plasmatic Zonulin and Expression of Intestinal Tight Junction Proteins in IBS Patients? | Biotech Hunter | Biotech Hunter