Comparative Study of the Efficacy of Oral Versus Intravenous Hydration as a Preventive Measure of Contrast-induced Nephropathy (CIN) in Patients With Renal Insufficiency (RI) Grade III Under Study Conducting Computed Tomography (CT)

PHASE3CompletedINTERVENTIONAL
Enrollment

264

Participants

Timeline

Start Date

July 4, 2017

Primary Completion Date

July 15, 2019

Study Completion Date

July 15, 2019

Conditions
Renal Insufficiency
Interventions
OTHER

Oral hydratation

500 mL of water two hours before computed tomography and 2000 milliliters 24 hours after performing computed tomography

DRUG

Bicarbonate endovenous hydratation

Intravenous hydration: sodium (1.6 molar) Bicarbonate 3 mL / kg / h starting one hour before the computed tomography and sodium bicarbonate (1/6 M) 1 mL / kg / h during the hour after computed tomography.

DRUG

Saline endovenous hydratation

If there is contraindication for administration of bicarbonate the pattern of intravenous hydration is performed with saline solution: 3 ml / kg / h for 1 hour before the procedure and normal saline 1 mL / kg / hour for hour after computed tomography.

Trial Locations (1)

08003

Hospital Clínic i Provincial de Barcelona, Barcelona

All Listed Sponsors
collaborator

Fundacion Clinic per a la Recerca Biomédica

OTHER

lead

David Garcia Cinca

OTHER

NCT02872155 - Comparative Study of the Efficacy of Oral Versus Intravenous Hydration as a Preventive Measure of Contrast-induced Nephropathy (CIN) in Patients With Renal Insufficiency (RI) Grade III Under Study Conducting Computed Tomography (CT) | Biotech Hunter | Biotech Hunter