195
Participants
Start Date
March 18, 2010
Primary Completion Date
March 1, 2031
Study Completion Date
March 1, 2031
Observation
no post operative chemotherapy
Etoposide
100 mg/m²/d, IV (in the vein) from D1 to D5.
Vincristine
1, 5 mg/m²/d, IV at D1.
Orbital irradiation
45 Grays (Standard or external beam radiotherapy).
Carboplatin
160 mg/m²/d, IV from D1 to D5.
Vincristine
1,5 mg/m²/d, IV at D22 and D26
Cyclophosphamide
300 mg/m²/d, IV from D22 to D26.
Carboplatin
560 mg/m²/d, IV at D1.
Etoposide
100 mg/m²/d, IV from D1 to D5
Carboplatin
160 mg/m²/d,IV from D1 to D5
Thiotepa
15 mg, intrathecal Thiotepa injection at D1.
Vincristine
1,5 mg/m²/d), IV at D22
Cyclophosphamide
1000 mg/m²/d, IV from D22 à D24.
Cytapheresis
Cytapheresis for peripheral blood stem cells collection after the primary or the secondary courses of Vincristine- Cyclophosphamid.
Carboplatin
AUC : 7/d, IV from D-8 to D-6.
Etoposide
250 mg/m²/d, IV from D -5 to D-3.
Thiotepa
300 mg/m²/d, IV from D-5 to D-3.
Peripheral bood stem cell transplantation
at D0
RECRUITING
Hopital D'Enfants La Timone, Marseille
RECRUITING
CHU CAEN, Caen
RECRUITING
Chu Bocage, Dijon
RECRUITING
Hopital Jean Minioz, Besançon
RECRUITING
Chu Morvan, Brest
RECRUITING
Chu Toulouse, Toulouse
RECRUITING
Chu R; Pellegrin, Bordeaux
RECRUITING
Hopital Arnaud de Villeneuve, Montpellier
RECRUITING
Chu de Rennes, Rennes
RECRUITING
Chu Tours, Tours
RECRUITING
Chu de Grenoble, Grenoble
RECRUITING
Chu Nantes, Nantes
RECRUITING
Chu Angers, Angers
RECRUITING
Chur de Reims, Reims
RECRUITING
Chu Nancy, Vandœuvre-lès-Nancy
RECRUITING
Centre Oscar Lambret, Lille
RECRUITING
Chu Estaing, Clermont-Ferrand
RECRUITING
Hoptial Hautepierre, Strasbourg
RECRUITING
Centre Leon Berard, Lyon
RECRUITING
Institut Curie, Paris
RECRUITING
Chu de Rouen, Rouen
RECRUITING
Hopital Nord Chu Amiens, Amiens
RECRUITING
Chu de Poitiers, Poitiers
RECRUITING
Chu Limoges, Limoges
RECRUITING
Chr Felix Guyon, Saint-Denis
RECRUITING
Chu Saint Etienne, Saint-Etienne
RECRUITING
Chu de Nice, Nice
Institut Curie
OTHER